| COVID-19 | 2020-04-27 | 17:00 Pacific |
| Coronavirus | also known as | SARS-CoV-2 |
| South Carolina Counties | Confirmed cases | Deaths |
| Abbeville | 29 | 0 |
| Aiken | 92 | 6 |
| Allendale | 8 | 1 |
| Anderson | 149 | 6 |
| Bamberg | 8 | 0 |
| Barnwell | 15 | 0 |
| Beaufort | 254 | 10 |
| Berkeley | 171 | 8 |
| Calhoun | 6 | 1 |
| Charleston | 435 | 6 |
| Cherokee | 15 | 0 |
| Chester | 27 | 0 |
| Chesterfield | 46 | 0 |
| Clarendon | 185 | 12 |
| Colleton | 26 | 4 |
| Darlington | 107 | 1 |
| Dillon | 44 | 0 |
| Dorchester | 92 | 2 |
| Edgefield | 25 | 1 |
| Fairfield | 33 | 2 |
| Florence | 268 | 10 |
| Georgetown | 39 | 2 |
| Greenville | 649 | 20 |
| Greenwood | 45 | 0 |
| Hampton | 22 | 0 |
| Horry | 209 | 12 |
| Jasper | 19 | 1 |
| Kershaw | 223 | 10 |
| Lancaster | 88 | 3 |
| Laurens | 35 | 1 |
| Lee | 55 | 6 |
| Lexington | 334 | 12 |
| Marion | 33 | 1 |
| Marlboro | 41 | 0 |
| McCormick | 6 | 1 |
| Newberry | 23 | 1 |
| Oconee | 24 | 0 |
| Orangeburg | 60 | 1 |
| Pickens | 53 | 0 |
| Richland | 840 | 19 |
| Saluda | 40 | 0 |
| Spartanburg | 255 | 8 |
| Sumter | 215 | 6 |
| Union | 25 | 0 |
| Williamsburg | 59 | 0 |
| York | 186 | 3 |
| South Carolina | 5613 | 177 |
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